Ischemia modified albumin is an indicator of oxidative stress in multiple sclerosis

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Ischemia modified albumin is an indicator of oxidative stress in multiple sclerosis

INTRODUCTION Oligodendrocytes need iron in processes of energy generation and myelination. However, excessive levels of iron may exert iron induced oxidative stress and thus lead to tissue degeneration. Monitoring oxidative stress will be of paramount importance in follow-up of patients with many diseases including multiple sclerosis (MS). The aim of this study was to measure total anti-oxidati...

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High ischemia-modified albumin concentration reflects oxidative stress but not myocardial involvement in systemic sclerosis.

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Curcumin ameliorates oxidative stress in animal models of multiple sclerosis

Background & Objectives: The role of oxidative stress in the pathogenesis of Multiple Sclerosis (MS) has been mentioned in previous studies. Curcumin is an active ingredient in Curcuma longa and has anti-inflammatory properties. The aim of this study was to investigate the effects of curcumin on reducing the oxidative stress in the animal model of MS. Materials & Methods: In this study, experim...

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Obesity is an independent determinant of ischemia-modified albumin.

OBJECTIVE We have measured ischemia-modified albumin (IMA), total antioxidant status (TAS), total oxidant status (TOS) and high-sensitivity C-reactive protein (hsCRP) levels in obese and normal-weight subjects to investigate if IMA can be used as a biomarker of oxidative stress and inflammation and if IMA was an independent determinant of obesity or not. METHODS The study was performed on 92 ...

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Ischemia modified albumin levels and oxidative stress in patients with bladder cancer.

BACKGROUND Impaired oxidative/antioxidative status plays an important role in the pathogenesis of many diseases like cancer. The aim of this study was to evaluate the levels of the novel marker ischemia modified albumin (IMA) and albumin adjusted-IMA (Adj-IMA) in patients with bladder cancer (BC) as well as its association with total antioxidant status (TAS), total oxidant status (TOS) and oxid...

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ژورنال

عنوان ژورنال: Biochemia Medica

سال: 2014

ISSN: 1846-7482

DOI: 10.11613/bm.2014.041